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  2. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    However ferritin levels may be elevated due to a variety of other causes including obesity, infection, inflammation (as an acute phase protein), chronic alcohol intake, liver disease, kidney disease, and cancer. [7] [32] [33] In males and postmenopausal females, normal range of serum ferritin is between 12 and 300 ng/mL (670 pmol/L) .

  3. Ferritin - Wikipedia

    en.wikipedia.org/wiki/Ferritin

    The ferritin levels measured usually have a direct correlation with the total amount of iron stored in the body. However, ferritin levels may be artificially high in cases of anemia of chronic disease, where ferritin is elevated in its capacity as an inflammatory acute phase protein and not as a marker for iron overload. [citation needed]

  4. Neuroferritinopathy - Wikipedia

    en.wikipedia.org/wiki/Neuroferritinopathy

    These oxidative molecules can cause oxidative brain damage. Iron that is bound to ferritin in nonreactive. [1] Fenton Reaction (1) Fe 2+ + H 2 O 2 → Fe 3+ + HO• + OH − (2) Fe 3+ + H 2 O 2 → Fe 2+ + HOO• + H + The ferritin protein is made up of heavy chain (H) and light chain (L) subunits. In neuroferritinopathy, the gene encoding the ...

  5. 65 Unsettling Medical Facts That Are Not For The Faint Of Heart

    www.aol.com/lifestyle/65-unsettling-medical...

    If you have restless legs syndrome, get a blood test for ferritin *now*. A level of 100 is recommended but doctors will sometimes say that as little as 40 is fine (edit: which the published ...

  6. Human iron metabolism - Wikipedia

    en.wikipedia.org/wiki/Human_iron_metabolism

    Iron can be stored in ferritin as ferric iron due to the ferroxidase activity of the ferritin heavy chain. [28] Dysfunctional ferritin may accumulate as hemosiderin, which can be problematic in cases of iron overload. [29] The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. [25]

  7. Hereditary haemochromatosis - Wikipedia

    en.wikipedia.org/wiki/Hereditary_haemochromatosis

    Haemochromatosis is protean in its manifestations, i.e., often presenting with signs or symptoms suggestive of other diagnoses that affect specific organ systems.Many of the signs and symptoms below are uncommon, and most patients with the hereditary form of haemochromatosis do not show any overt signs of disease nor do they have premature morbidity, if they are diagnosed early, but, more ...

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