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  2. Hypothalamic disease - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic_disease

    Hypothalamic disease is a disorder presenting primarily in the hypothalamus, which may be caused by damage resulting from malnutrition, including anorexia and bulimia eating disorders, [1] [2] genetic disorders, radiation, surgery, head trauma, [3] lesion, [1] tumour or other physical injury to the hypothalamus. The hypothalamus is the control ...

  3. What Is Low Testosterone & What Causes It? - AOL

    www.aol.com/low-testosterone-causes-125700734.html

    The process goes like this: The hypothalamus produces and releases gonadotropin-releasing hormone (GnRH). ... Low testosterone levels can sometimes result in gynecomastia — a form of breast ...

  4. Warburg hypothesis - Wikipedia

    en.wikipedia.org/wiki/Warburg_hypothesis

    Scientist Otto Warburg, whose research activities led to the formulation of the Warburg hypothesis for explaining the root cause of cancer.. The Warburg hypothesis (/ ˈ v ɑːr b ʊər ɡ /), sometimes known as the Warburg theory of cancer, postulates that the driver of carcinogenesis (cancer formation) is insufficient cellular respiration caused by insult (damage) to mitochondria. [1]

  5. Vasopressin - Wikipedia

    en.wikipedia.org/wiki/Vasopressin

    The physiological stimulus for secretion of vasopressin is increased osmolality of the plasma, monitored by the hypothalamus. A decreased arterial blood volume , (such as can occur in cirrhosis , nephrosis , and heart failure ), stimulates secretion, even in the face of decreased osmolality of the plasma: it supersedes osmolality, but with a ...

  6. Causes of cancer - Wikipedia

    en.wikipedia.org/wiki/Causes_of_cancer

    Adipose tissue dysregulation can result in oxidative stress leading to oxidative DNA damage and cancer associated genetic instability. [57] Physical inactivity is believed to contribute to cancer risk not only through its effect on body weight but also through negative effects on immune system and endocrine system. [34]

  7. Carcinogenesis - Wikipedia

    en.wikipedia.org/wiki/Carcinogenesis

    The central role of DNA damage and epigenetic defects in DNA repair genes in carcinogenesis. DNA damage is considered to be the primary cause of cancer. [17] More than 60,000 new naturally-occurring instances of DNA damage arise, on average, per human cell, per day, due to endogenous cellular processes (see article DNA damage (naturally occurring)).

  8. Cyclin-dependent kinase 5 - Wikipedia

    en.wikipedia.org/wiki/Cyclin-dependent_kinase_5

    Multiple sclerosis (MS): [30] is one of the diseases, in which a failure of remyelination [31] can provoke lasting axonal damage and an irreversible loss of function. Cyclin-dependent kinase 5 is involved in the process as it regulates the oligodendrocyte (OL9 development and myelination in CNS). Cdk5 inhibitors impede the remyelination and ...

  9. Hypothalamic obesity - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic_Obesity

    It can also result from injuries to the hypothalamus either from trauma, therapeutic radiation, brain surgery, and especially craniopharyngioma and its treatments. Possible treatments include bariatric surgery and melanocortin 4 receptor agonists such as setmelanotide. [1] [2] [3] [4]

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