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Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. They are called C cells because the primary function of these cells is to secrete calcitonin. [1] They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells.
The parathyroid glands are variable in number: three or more small glands, [5] and can usually be located on the posterior surface of the thyroid gland. [5] Occasionally, some individuals may have six, eight, or even more parathyroid glands. [3] Rarely, the parathyroid glands may be within the thyroid gland itself, the chest, or even the thymus ...
Chief cells in parathyroid adenomas also display acid phosphatase activity. [5] It is a benign tumor of the gland that requires surgical removal. [13] These benign adenomas are typically affect only one or two of the parathyroid glands, known respectively as a single adenoma or double adenoma. Typically, no disease is linked to the cause. [14]
Hyperparathyroidism, in general, is caused by either tumorous growth in one or more parathyroid glands or a prolonged decrease in blood calcium levels or hypocalcaemia which in turn stimulates the production of parathyroid hormone release from the parathyroid gland. [10] [11] The parathyroid gland is located beside the thyroid gland in the neck ...
There are many variants in the size and shape of the thyroid gland, and in the position of the embedded parathyroid glands. [5] Sometimes there is a third lobe present called the pyramidal lobe. [5] When present, this lobe often stretches up to the hyoid bone from the thyroid isthmus and may be one to several divided lobes. [4]
[1] The hypothalamic–pituitary–thyroid axis (HPT axis for short, a.k.a. thyroid homeostasis or thyrotropic feedback control) is part of the neuroendocrine system responsible for the regulation of metabolism and also responds to stress. As its name suggests, it depends upon the hypothalamus, the pituitary gland, and the thyroid gland.
Thyroid disease is a medical condition that affects the structure and/or function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to ...
The thyroid system of the thyroid hormones T 3 and T 4 [1] Thyroid hormones are two hormones produced and released by the thyroid gland, triiodothyronine (T 3) and thyroxine (T 4). They are tyrosine-based hormones that are primarily responsible for regulation of metabolism. T 3 and T 4 are partially composed of iodine, derived from food. [2]