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Enoxaparin sodium, sold under the brand name Lovenox among others, is an anticoagulant medication (blood thinner). [11] It is used to treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) including during pregnancy and following certain types of surgery. [ 11 ]
Model-Informed Precision Dosing (MIPD for short) is the use of pharmacometric models with computer software to optimize drug dosage for an individual patient. [1]Developed in the late 1960s under the impetus of clinical pharmacologists such as Lewis Sheiner and Roger Jelliffe, these approaches involve applying the equations and parameters describing a drug's pharmacokinetics and ...
So, the maintenance dose of foosporin is 100 milligrams (100 mg) per day—just enough to offset the amount cleared. Suppose a patient just started taking 100 mg of foosporin every day. On the first day, they'd have 100 mg in their system; their body would clear 10 mg, leaving 90 mg.
Average molecular weight: heparin is about 15 kDa, and LMWH is about 4.5 kDa. [25] Less frequent subcutaneous dosing than for heparin for postoperative prophylaxis of venous thromboembolism. Once or twice daily subcutaneous injection for treatment of venous thromboembolism and in unstable angina instead of intravenous infusion of high-dose heparin.
Compared to traditional metrics, such as the body mass index (BMI), (which uses weight and height), BRI may improve predictions of the amount of body fat and the volume of visceral adipose tissue. Despite its common use, BMI can misclassify individuals as obese because it does not distinguish between a person's lean body mass and fat mass ...
The corpulence index yields valid results even for very short and very tall persons, [7] which is a problem with BMI — for example, an ideal body weight for a person 152.4 cm tall (48 kg) will render BMI of 20.7 and CI of 13.6, while for a person 200 cm tall (99 kg), the BMI will be 24.8, very close to the "overweight" threshold of 25, while ...
The Harris–Benedict equation (also called the Harris-Benedict principle) is a method used to estimate an individual's basal metabolic rate (BMR).. The estimated BMR value may be multiplied by a number that corresponds to the individual's activity level; the resulting number is the approximate daily kilocalorie intake to maintain current body weight.
The estimations in the above tables are based weight and height data from the U.S. NCHS National Health and Nutrition Examination Survey (2011-2014). [ 18 ] There was an average BSA of 1.73 m 2 for 3,000 cancer patients from 1990 to 1998 in a European Organisation for Research and Treatment of Cancer (EORTC) database.