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The spinothalamic tract is a nerve tract in the anterolateral system in the spinal cord. [1] This tract is an ascending sensory pathway to the thalamus . From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus .
The anterolateral system (ALS) is a bundle of afferent somatosensory fibers from different ascending tracts in the spinal cord. These fibers include those of the spinomesencephalic tract, spinothalamic tract, and spinoreticular tract amongst others. [5] Spinomesencephalic fibres project to the periaqueductal gray, and to the tectum.
The spinohypothalamic tract or spinohypothalamic fibers is a sensory fiber tract projecting from the spinal cord to the hypothalamus directly to mediate reflex autonomic and endocrine responses to painful stimuli (the hypothalamus receives additional indirect nociceptive projections from the reticular formation (see: spinoreticular tract), and periaqueductal gray (see: spinomesencephalic tract).
The ventral posterolateral nucleus (VPL) is one of the subdivisions of the ventral posterior nucleus in the ventral nuclear group of the thalamus. [1] It relays sensory information from the second-order neurons of the neospinothalamic tract and medial lemniscus (of the dorsal column-medial lemniscus pathway) which synapse with the third-order neurons in the nucleus.
The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints.
The ascending pain and temperature fibers of the spinothalamic tract send information to the PAG via the spinomesencephalic pathway (so-named because the fibers originate in the spine and terminate in the PAG, in the mesencephalon or midbrain). This region has been used as the target for brain-stimulating implants in patients with chronic pain.
In neuroanatomy, a neural pathway is the connection formed by axons that project from neurons to make synapses onto neurons in another location, to enable neurotransmission (the sending of a signal from one region of the nervous system to another). Neurons are connected by a single axon, or by a bundle of axons known as a nerve tract, or ...
The hypothalamospinal tract is an unmyelinated [1] non-decussated [2] descending nerve tract that arises in the hypothalamus and projects to the brainstem and spinal cord to synapse with pre-ganglionic autonomic (both sympathetic and parasympathetic) neurons.