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Vedolizumab is a gut-selective, Alpha-4 Beta-7 anti-integrin, monoclonal antibody that was approved by the U.S. Food and Drug Administration to treat Crohn's disease in 2014. It is indicated for management of moderate-to-severe, active Crohn's disease patients and it works by inhibiting the trafficking of pro-inflammatory immune cells to the ...
Historically, before there were effective medications for the treatment of Crohn’s disease, the majority of Crohn’s patients needed surgery to address complications that would inevitably arise ...
A low-fiber diet may be used to prepare for or recover from various medical procedures: [1] [2] [4] [5] Abdominal surgery; Colonoscopy; Internal hemorrhoid surgery; A low-fiber diet may also be used during acute stages of the following conditions, to rest the bowels: [1] [2] [4] [5] Bowel inflammation; Crohn's disease; Diverticulitis ...
Crohn's disease can be problematic during pregnancy, and some medications can cause adverse outcomes for the fetus or mother. Consultation with an obstetrician and gastroenterologist about Crohn's disease and all medications facilitates preventive measures. In some cases, remission occurs during pregnancy.
Mirikizumab, a drug currently approved by the Food and Drug Administration (FDA) for the treatment of ulcerative colitis, also sends Crohn's disease into clinical remission, new findings suggest.
The anti-TNF-α monoclonal antibody infliximab is a major biological therapy for inflammatory bowel disease. Biological therapy, the use of medications called biopharmaceuticals or biologics that are tailored to specifically target an immune or genetic mediator of disease, plays a major role in the treatment of inflammatory bowel disease. [1]