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In general, neuroglial cells are smaller than neurons. There are approximately 85 billion glia cells in the human brain, [8] about the same number as neurons. [8] Glial cells make up about half the total volume of the brain and spinal cord. [27] The glia to neuron-ratio varies from one part of the brain to another.
Glial stem cells are found in all parts of the adult brain. [1] Glial cells greatly outnumber neurons and apart from their supporting role to neurons, glia – astrocytes in particular have been acknowledged as being able to communicate with neurons involving a signalling process similar to neurotransmission called gliotransmission. [4]
It is composed of neurons, also known as nerve cells, which receive and transmit impulses to and from it , and neuroglia, also known as glial cells or glia, which assist the propagation of the nerve impulse as well as provide nutrients to the neurons. [1] Nervous tissue is made up of different types of neurons, all of which have an axon.
Schwann cells or neurolemmocytes (named after German physiologist Theodor Schwann) are the principal glia of the peripheral nervous system (PNS). Glial cells function to support neurons and in the PNS, also include satellite cells, olfactory ensheathing cells, enteric glia and glia that reside at sensory nerve endings, such as the Pacinian corpuscle.
Thus, the fundamental difference between a neuron and a nonneuronal cell is a matter of degree. Another major class of cells found in the nervous system are glial cells. These cells are only recently beginning to receive attention from neurobiologists for being involved not just in nourishment and support of neurons, but also in modulating ...
From studies on rats and mice, researchers have found that satellite glial cells express many neurotransmitter receptors, such as muscarinic acetylcholine and erythropoietin receptors. [2] In order to differentiate between SGCs and other glial cells researchers have used markers to identify which proteins are found in different cells.
Neurons are the primary components of the nervous system, along with the glial cells that give them structural and metabolic support. [5] The nervous system is made up of the central nervous system , which includes the brain and spinal cord , and the peripheral nervous system , which includes the autonomic , enteric and somatic nervous systems ...
The new neurons generated by the neuroepithelial cells, progenitors and radial glial cells will not survive unless they are able to integrate into the system by making connections with new neighbors. This also leads to many controversial concepts, like neurogenic therapy involving the transplant of local progenitor cells to a damaged area.