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Mometasone, also known as mometasone furoate, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. [ 10 ] [ 11 ] [ 12 ] Specifically it is used to prevent rather than treat asthma attacks. [ 10 ]
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2-Furoyl chloride is an acyl chloride of furan.It takes the form of a corrosive liquid, which is more irritating to the eyes than benzoyl chloride. [1] 2-Furoyl chloride is a useful pharmaceutical intermediate and is used in the synthesis of mometasone furoate, an antiinflammatory prodrug used in the treatment of skin disorders, hay fever and asthma.
The methasones (or metasones) are a class of corticosteroids [1] which are generally used in dermatology.They are defined by substitution with a methyl group at the C16α or C16β position of the pregnane steroid nucleus.
It is the first asthma triple-combination therapy; it consists of a fixed-dose combination of three active substances (indacaterol, glycopyrronium bromide and mometasone furoate) in capsules, to be administered using an inhaler. [11] An optional electronic sensor may also be co-packed with the product. [11]
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[1] [2] [3] It contains olopatadine hydrochloride and mometasone furoate monohydrate. [1] [2] It is sprayed into the nose. [1] [2] Common side effects include an unpleasant taste . [1] It was approved for medical use in Australia in December 2019, [1] [4] and in the United States in January 2022. [2]