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For transgender men on testosterone, physical changes include achieving a more masculine appearance (resulting in facial hair, a lower voice and other desired effects), while for transgender women ...
Bone is not static. It is constantly being reabsorbed and created. Osteoporosis results when bone formation occurs at a rate less than bone resorption. Estrogen is the predominant sex hormone that slows bone loss (even in men). Both estrogen and testosterone help stimulate bone formation (T, especially at puberty).
Estrogens act by binding to and activating the estrogen receptor (ER), their biological target in the body. [14] A variety of different forms of estrogens are available and used medically. [ 14 ] The most common estrogens used in transgender women include estradiol , which is the predominant natural estrogen in women, and estradiol esters such ...
Gender-affirming hormone therapy (GAHT), also called hormone replacement therapy (HRT) or transgender hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.
Menopause is associated with a rapid decline of estrogen, as well as a steady rate of decline of androgens. [12] The decline of estrogen and androgen levels is believed to account for the lowered levels of sexual desire and motivation in postmenopausal women, although the direct relationship is not well understood.
For women, a drop in estrogen can cause weight gain, particularly in the abdomen (aka menopause belly). For men, low testosterone is linked to an increase in fat mass. Men with obesity are more ...
What’s more, men with low levels of testosterone at baseline saw an increase in testosterone when taking 5-alpha-reductase inhibitors, but men with high levels of testosterone at baseline didn ...
Estradiol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. [10] Due to its estrogenic activity, estradiol has antigonadotropic effects and can inhibit fertility and suppress sex hormone production in both women and men.