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A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion [1]) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. [2] The axons of dorsal root ganglion neurons are known as afferents.
The dorsal root of spinal nerve (or posterior root of spinal nerve or sensory root) [1] is one of two "roots" which emerge from the spinal cord. It emerges directly from the spinal cord, and travels to the dorsal root ganglion. Nerve fibres with the ventral root then combine to form a spinal nerve. The dorsal root transmits sensory information ...
The body is situated in the dorsal root ganglion, with one axon traveling peripherally to tissue, and one traveling into the dorsal column. On the right is a bipolar neuron . When an action potential is generated by a mechanoreceptor in the tissue , the action potential will travel along the peripheral axon of the first-order neuron.
The posterior thoracic nucleus is a major relay center for unconscious proprioception.Sensory information from muscle spindles and tendon organs is carried by axons of larger neurons in dorsal root ganglia, which synapse onto neurons in the spinal cord including the posterior thoracic nucleus.
Just outside the spinal cord, thousands of afferent neuronal cell bodies are aggregated in a swelling in the dorsal root known as the dorsal root ganglion. [1] [2] All of the axons in the dorsal root, which contains afferent nerve fibers, are used in the transduction of somatosensory information.
Dorsal root ganglion neurons differentiate from neural crest progenitors. As the dorsal and ventral column cells proliferate, the lumen of the neural tube narrows to form the small central canal of the spinal cord. [16] The alar plate and the basal plate are separated by the sulcus limitans. Additionally, the floor plate also secretes netrins.
The posterolateral tract contains centrally projecting axons from dorsal root ganglion cells carrying peripheral pain and temperature information (location, intensity and quality). These axons enter the spinal column and penetrate the grey matter of the dorsal horn, where they synapse on second-order neurons in either the substantia gelatinosa ...
Its neurons receive afferent input from dorsal root ganglia sensory neurons of the lower torso and the lower limbs. [5] The gracile nucleus and gracile fasciculus carry epicritic , kinesthetic , and conscious proprioceptive information from the lower part of the body (below the level of T6 in the spinal cord).