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Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins. [5] IL-9 is produced by variety of cells like mast cells , NKT cells, Th2 , Th17 , Treg , ILC2 , and Th9 cells in different amounts.
In cell biology, T H 9 cells (T helper type 9 cells, CD4+IL-9+IL-13−IFNγ − ) are a sub-population of CD4+T cells that produce interleukin-9 (IL-9). They play a role in defense against helminth infections , in allergic responses , in autoimmunity , and tumor suppression.
Interleukin 9 (IL-9) [30] is a cytokine that supports IL-2 independent and IL-4 independent growth of helper T cells. Early studies had indicated that Interleukin 9 and 7 seem to be evolutionary related [31] and Pfam, InterPro and PROSITE entries exist for interleukin 7
Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also denotes its human gene. [5] The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as ...
Interleukin 2 and interleukin 10 production has been reported in activated T h 1 cell. [25] Interleukin 4, interleukin 5, interleukin 6, interleukin 9, interleukin 10, interleukin 13: Immune stimulation promoted: Cellular immune system. Maximizes the killing efficacy of the macrophages and the proliferation of cytotoxic CD8 + T cells. Also ...
Interleukins are produced by lymphocytes, among other cell types, and are released in response to antigenic and non-antigenic stimuli. The gene IL2RG codes for the common gamma chain protein, which is a common subunit of the individual receptors for Interleukin 2, Interleukin 4, Interleukin 7, Interleukin 9, Interleukin 15 and Interleukin 21. [10]