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CA3 has been implicated in a number of working theories on memory and hippocampal learning processes. Slow oscillatory rhythms (theta-band; 3–8 Hz) are cholinergically driven patterns that depend on coupling of interneurons and pyramidal cell axons via gap junctions, as well as glutaminergic (excitatory) and GABAergic (inhibitory) synapses.
The third important theory of hippocampal function relates the hippocampus to space, and spatial memory, with the idea of a cognitive map first proposed by American psychologist E.C. Tolman. This theory was followed further by O'Keefe, and in 1971, he and his student Dostrovsky discovered neurons, in the rat hippocampus that seemed to show ...
The medial temporal lobe structures are critical for long-term memory, and include the hippocampal formation, perirhinal cortex, parahippocampal, and entorhinal neocortical regions. [4]: 196 [5] The hippocampus is critical for memory formation, and the surrounding medial temporal cortex is currently theorized to be critical for memory storage.
Hippocampus in the human brain Nissl-stained coronal section of the brain of a macaque monkey, showing hippocampal formation and subfields (circled). Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of each cerebral hemisphere of the brain.
The hippocampus is a structure in the brain that has been associated with various memory functions. It is part of the limbic system , and lies next to the medial temporal lobe. It is made up of two structures, the Ammon's Horn , and the Dentate gyrus , each containing different types of cells .
The hippocampus is located in the medial temporal lobe (subcortical), and is an infolding of the medial temporal cortex. [1] The hippocampus plays an important role in the transfer of information from short-term memory to long-term memory during encoding and retrieval stages. These stages do not need to occur successively, but are, as studies ...
It is an integral part of the limbic system, which is involved with emotion formation and processing, [1] learning, [2] and memory. [ 3 ] [ 4 ] The combination of these three functions makes the cingulate gyrus highly influential in linking motivational outcomes to behavior (e.g. a certain action induced a positive emotional response, which ...
View of left entorhinal cortex (red) from beneath the brain, with front of brain at top. Artist's rendering. The superficial layers – layers II and III – of EC project to the dentate gyrus and hippocampus: Layer II projects primarily to dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the subiculum.