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Pramipexole is used in the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS). [8] Safety in pregnancy and breastfeeding is unknown. [1] A 2008 meta-analysis found that Pramipexole was more effective than Ropinirole in the treatment of RLS. [12] It is occasionally prescribed off-label for depression.
Ropinirole is also known to cause an effect known as "augmentation" when used to treat restless legs syndrome, where over time treatment with dopamine agonists will cause restless legs syndrome symptoms to become more severe. This usually leads to constant dosage increases in an attempt to offset the symptom progression.
Rotigotine, sold under the brand name Neupro among others, is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease and restless legs syndrome. [3] [4] It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours. [3]
Restless Legs Syndrome Awareness Day is Sept. 23. The condition can make it hard to sleep, but a simple treatment can help. What 4 experts who treat people with restless legs syndrome want you to ...
Other uses include for dopamine-responsive dystonia (DRD) and restless legs syndrome. [10] [17] [18] Using carbidopa/levodopa may lead to augmentation syndrome, with increasing persistence of restless legs syndrome, and increasing severity. [18] There is tentative evidence that it is useful in amblyopia when used with other treatments. [19]
Restless legs syndrome (RLS), (also known as Willis–Ekbom disease (WED), is a neurological disorder, usually chronic, that causes an overwhelming urge to move one's legs. [ 2 ] [ 10 ] There is often an unpleasant feeling in the legs that improves temporarily by moving them. [ 2 ]
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