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Thrombotic thrombocytopenic purpura (TTP) initially presents with a range of symptoms that may include severe thrombocytopenia (platelet count usually < 30,000/mm³), microangiopathic hemolytic anemia (evidenced by schistocytes in the blood smear), and various clinical signs such as petechiae, purpura, neurologic symptoms, myocardial ischemia ...
Harris platelet syndrome (associated with giant platelet disorder) Macrothrombocytopenia and hearing loss; May–Hegglin anomaly (associated with giant platelet disorder) MYH9-related disease (associated with giant platelet disorder) PRKACG-related thrombocytopenia; Paris-Trousseau thrombocytopenia/Jacobsen syndrome; Sebastian syndrome; SLFN14 ...
Diagnosis is done by the help of symptoms and only blood count abnormality is thrombocytopenia. [citation needed] Treatment. This section is empty.
Unlike ITP, the platelet count in gestational thrombocytopenia rarely goes below 100,000, and a platelet count below 80,000 is even more rare (seen in less than 0.1% of cases of gestational thrombocytopenia). Also unlike ITP, gestational thrombocytopenia is not a cause of neonatal or maternal bleeding, or neonatal thrombocytopenia. [63]
The 4T score for heparin-induced thrombocytopenia [9] [10] Thrombocytopenia 2 points if the fall in platelet count is >50% of the previous value, AND the lowest count (nadir) is 20–100 × 10 9 /liter 1 point if the fall is 30–50% or the nadir is 10–19 × 10 9 /liter No points if the fall is less than 30% or the nadir is <10 × 10 9 /liter ...
Additionally, platelet antigen genotyping can be performed on the maternal and paternal blood to determine the exact nature of the incompatibility. [citation needed] Neonatal platelet counts on laboratory testing are typically under 20,000 μL −1. Higher counts may suggest a different diagnosis, such as maternal immune thrombocytopenic ...
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