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  2. Phenylpropanolamine - Wikipedia

    en.wikipedia.org/wiki/Phenylpropanolamine

    Phenylpropanolamine was first synthesized in the early 20th century, in or around 1910. [21] [11] It was patented as a mydriatic in 1913. [21] The pressor effects of phenylpropanolamine were characterized in the late 1920s and the 1930s. [21] Phenylpropanolamine was first introduced for medical use by the 1930s. [23] [11]

  3. Promethazine - Wikipedia

    en.wikipedia.org/wiki/Promethazine

    In Germany, it is approved for the treatment of agitation and agitation associated with underlying psychiatric disorders with a maximum daily dose of 200 mg. [14] For nausea and vomiting associated with anesthesia or chemotherapy. It is commonly used postoperatively as an antiemetic. The antiemetic activity increases with increased dosing ...

  4. Verapamil - Wikipedia

    en.wikipedia.org/wiki/Verapamil

    Verapamil is also used for the treatment of angina (chronic stable, vasospastic or Prinzmetal variant), unstable angina (crescendo, preinfarction), and for the prevention of paroxysmal supraventricular tachycardia (PSVT). [18] Verapamil is a class-IV antiarrhythmic and more effective than digoxin in controlling ventricular rate. [19]

  5. Propranolol - Wikipedia

    en.wikipedia.org/wiki/Propranolol

    Propranolol is not recommended for the treatment of high blood pressure by the Eighth Joint National Committee (JNC 8) because a higher rate of the primary composite outcome of cardiovascular death, myocardial infarction, or stroke compared to an angiotensin receptor blocker was noted in one study.

  6. These Companies Paid Massive Sums to Settle Lawsuits - AOL

    www.aol.com/26-biggest-lawsuit-settlements...

    Drugmaker Vitaris agreed to pay big to settle a lawsuit over the EpiPen, a critical treatment for severe allergic reactions. The suit alleged that Vitaris, then known as Mylan, tried to delay ...

  7. Phentolamine - Wikipedia

    en.wikipedia.org/wiki/Phentolamine

    The primary application for phentolamine is for the control of hypertensive emergencies, most notably due to pheochromocytoma. [5]It also has usefulness in the treatment of cocaine-induced cardiovascular complications, where one would generally avoid β-blockers (e.g. metoprolol), as they can cause unopposed α-adrenergic mediated coronary vasoconstriction, worsening myocardial ischemia and ...

  8. Phenylpropylamine - Wikipedia

    en.wikipedia.org/wiki/Phenylpropylamine

    Phenylpropylamine, also known as 3-phenylpropylamine, is a monoamine releasing agent (MRA) related to phenethylamine (2-phenylethylamine). [1] [2] It is the analogue of phenethylamine in which the ethylamine side chain has been lengthened by one carbon atom to instead be a propylamine chain.

  9. Pitolisant - Wikipedia

    en.wikipedia.org/wiki/Pitolisant

    Pitolisant, sold under the brand name Wakix among others, is a medication used for the treatment of excessive daytime sleepiness in adults with narcolepsy. [3] It is an inverse agonist of the histamine H 3 receptor. [3]