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A leiomyosarcoma (LMS) is a rare malignant (cancerous) smooth muscle tumor. [1] The word is from leio- 'smooth' myo- 'muscle' and sarcoma 'tumor of connective tissue'. The stomach, bladder, uterus, blood vessels, and intestines are examples of hollow organs made up of smooth muscles where LMS can be located; however, the uterus and abdomen are the most common sites.
Uterine sarcoma is rare and mostly occurs in post-menopausal women. The most common type, leiomyosarcoma, is twice as common in Black women as it is in white women. Uterine sarcoma condition is most commonly treated by radical hysterectomy. If cancer has spread beyond the uterus, radiation, chemotherapy, and hormonal therapy may be used.
It predisposes individuals to renal cell cancer, an association denominated hereditary leiomyomatosis and renal cell cancer. [1] [2] It is also associated with increased risk of uterine leiomyosarcoma. [3] The syndrome is caused by a mutation in the fumarate hydratase gene, which leads to an accumulation of fumarate.
However, a small proportion of uterine fibroids can mimic other malignant uterine tumors (e.g. leiomyosarcoma) on all available imaging modalities (e.g. ultrasound, CT, MRI and PET-CT). [37] Malignant tumors of the uterine wall (e.g. leiomyosarcoma) are very rare.
Uterine cancer, also known as womb cancer, includes two types of cancer that develop from the tissues of the uterus. [3] Endometrial cancer forms from the lining of the uterus, and uterine sarcoma forms from the muscles or support tissue of the uterus. [1] [2] Endometrial cancer accounts for approximately 90% of all uterine cancers in the ...
The Cancer Imaging Archive (TCIA) is an open-access database of medical images for cancer research. The site is funded by the National Cancer Institute's (NCI) Cancer Imaging Program, and the contract is operated by the University of Arkansas for Medical Sciences. Data within the archive is organized into collections which typically share a ...
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