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  2. Guanidinoacetate methyltransferase deficiency - Wikipedia

    en.wikipedia.org/wiki/Guanidinoacetate_methyl...

    Despite treatment, none of the patients have been reported to return to completely normal developmental level, if significant damage had taken place before treatment. [8] Prior to the addition of GAMT deficiency to newborn screening panels, younger siblings of affected individuals may have been tested at birth and treated early. [ 24 ]

  3. Acidosis - Wikipedia

    en.wikipedia.org/wiki/Acidosis

    Metabolic acidosis is compensated for in the lungs, as increased exhalation of carbon dioxide promptly shifts the buffering equation to reduce metabolic acid. This is a result of stimulation to chemoreceptors , which increases alveolar ventilation , leading to respiratory compensation, otherwise known as Kussmaul breathing (a specific type of ...

  4. Metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_acidosis

    Metabolic acidosis is a serious electrolyte disorder characterized by an imbalance in the body's acid-base balance.Metabolic acidosis has three main root causes: increased acid production, loss of bicarbonate, and a reduced ability of the kidneys to excrete excess acids. [5]

  5. Hyperchloremic acidosis - Wikipedia

    en.wikipedia.org/wiki/Hyperchloremic_acidosis

    In general, the cause of a hyperchloremic metabolic acidosis is a loss of base, either a gastrointestinal loss or a renal loss [citation needed]. Gastrointestinal loss of bicarbonate (HCO − 3) [citation needed] Severe diarrhea (vomiting will tend to cause hypochloraemic alkalosis) Pancreatic fistula with loss of bicarbonate rich pancreatic fluid

  6. Zoledronic acid - Wikipedia

    en.wikipedia.org/wiki/Zoledronic_acid

    Zoledronic acid is indicated for the prevention of skeletal related events (pathological fractures, spinal compression, radiation or surgery to bone, or tumor-induced hypercalcemia) in people with advanced malignancies involving bone; the treatment of adults with tumor-induced hypercalcemia (TIH).

  7. High anion gap metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/High_anion_gap_metabolic...

    High anion gap metabolic acidosis is typically caused by acid produced by the body. More rarely, it may be caused by ingesting methanol or overdosing on aspirin . [ 1 ] [ 2 ] The delta ratio is a formula that can be used to assess elevated anion gap metabolic acidosis and to evaluate whether mixed acid base disorder (metabolic acidosis) is present.

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