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The genus Klebsiella was named after the German microbiologist Edwin Klebs (1834–1913). [citation needed] It is also known as Friedlander's bacillum in honor of Carl Friedländer, a German pathologist, who proposed that this bacterium was the etiological factor for the pneumonia seen especially in immunocompromised individuals such as people with chronic diseases or alcoholics.
The evolution of bacteria on a "Mega-Plate" petri dish A list of antibiotic resistant bacteria is provided below. These bacteria have shown antibiotic resistance (or antimicrobial resistance). Gram positive Clostridioides difficile Clostridioides difficile is a nosocomial pathogen that causes diarrheal disease worldwide. Diarrhea caused by C. difficile can be life-threatening. Infections are ...
Klebsiella organisms can lead to a wide range of disease states, notably pneumonia, urinary tract infections, sepsis, meningitis, diarrhea, peritonitis and soft tissue infections. [ 6 ] [ 11 ] Klebsiella species have also been implicated in the pathogenesis of ankylosing spondylitis and other spondyloarthropathies . [ 12 ]
The class A Klebsiella pneumoniae carbapenemase is currently the most common carbapenemase, which was first detected in North Carolina, United States, in 1996 and has since spread worldwide. [12] A later publication indicated that Enterobacteriaceae that produce KPC were becoming common in the United States. [13])
ESKAPE is an acronym comprising the scientific names of six highly virulent and antibiotic resistant bacterial pathogens including: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. [1] The acronym is sometimes extended to ESKAPEE to include Escherichia coli. [2]
A 2008 study at Mount Sinai identified outcomes associated with Carbapenem-resistant Klebsiella pneumoniae infections, in which patients in need of organ or stem cell transplants, mechanical ventilation, prolonged hospitalization, or prior treatment with carbapenems, had an increased probability of infection with Carbapenem-resistant K ...
As of February 2009, the class A Klebsiella pneumoniae carbapenemase globally has been the most common carbapenemase, and was first detected in 1996 in North Carolina, USA. [31] A 2010 publication indicated that KPC producing Enterobacteriaceae were becoming common in the United States. [32]
A review of investigational antibiotics shows that several new agents will become available in the coming years, even though the pace of antimicrobial research has proven far too slow. Overuse of antimicrobial agents and problems with infection control practices have led to the development of multidrug-resistant gram-negative bacterial infections.