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Gelesis100 is an oral superabsorbent hydrogel, which is produced from carboxymethylcellulose and citric acid. [1] [9] The cross-linked product forms a hydrophilic matrix, which absorbs water. [1] Taken in capsule form by mouth, [10] as Gelesis100 absorbs water, it expands in the stomach and small intestine.
A suppository is a dosage form used to deliver medications by insertion into a body orifice (any opening in the body), where it dissolves or melts to exert local or systemic effects. There are three types of suppositories, each to insert into a different sections: rectal suppositories into the rectum , vaginal suppositories into the vagina ...
Enteric coated tablets are designed to dissolve in the intestine, not the stomach, because the drug present in the tablet causes irritation in the stomach. Administering medication rectally. The rectal route is an effective route of administration for many medications, especially those used at the end of life.
Typically, in these measurements the one side of the hydrogel is subjected to a sinusoidal load in shear mode while the applied stress is measured with a stress transducer and the change in sample length is measured with a strain transducer. [43] One notation used to model the sinusoidal response to the periodic stress or strain is:
In hydrogels, structure and stability of water molecules are highly affected by the bonds. The polar groups in the polymer strongly bind water molecules and form hydrogen bonds which also cause hydrophobic effects to occur. [4] These hydrophobic effects can be exploited to design physically crosslinked hydrogels that exhibit self healing abilities.
Sustained-release dosage forms are dosage forms designed to release (liberate) a drug at a predetermined rate in order to maintain a constant drug concentration for a specific period of time with minimum side effects. This can be achieved through a variety of formulations, including liposomes and drug-polymer conjugates (an example being ...
Hydrogel dressing is a medical dressing based on hydrogels, three-dimensional hydrophilic structure. [1] The insoluble hydrophilic structures absorb polar wound exudates and allow oxygen diffusion at the wound bed to accelerate healing. [ 2 ]
An upturned vial of hair gel Silica gel. A gel is a semi-solid that can have properties ranging from soft and weak to hard and tough. [1] [2] Gels are defined as a substantially dilute cross-linked system, which exhibits no flow when in the steady state, although the liquid phase may still diffuse through this system.