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Repeated administration of a medication is also different from single dosing, as many drugs have active metabolites that can build up in the body. [6] Patient variables such as sex, age, and organ function may also influence the effect of the drug on the system. These variables are rarely included in equianalgesic charts. [7] [3] [8]
Clonazepam, sold under the brand name Klonopin among others, is a benzodiazepine medication used to prevent and treat anxiety disorders, seizures, bipolar mania, agitation associated with psychosis, obsessive–compulsive disorder (OCD), and akathisia. [11] It is a long-acting [12] tranquilizer of the benzodiazepine class. [11]
The consensus is to reduce dosage gradually over several weeks, e.g. 4 or more weeks for diazepam doses over 30 mg/day, [1] with the rate determined by the person's ability to tolerate symptoms. [120] The recommended reduction rates range from 50% of the initial dose every week or so, [121] to 10–25% of the daily dose every 2 weeks. [120]
Impressed by the medical treatment received by members of Jacksonville's Davis family (then owners of the Winn-Dixie supermarket chain) at Mayo Clinic in Minnesota, they rallied community and corporate support to bring Mayo Clinic to Jacksonville and donated a 392-acre parcel off San Pablo Road on which Mayo Clinic opened an outpatient consultation center on October 6th, 1986.
Service dog for a boy with autism and seizures calms him during hospital stay. A seizure response dog (SRD) (also known as seizure dog) is a dog demonstrating specific assisting behaviour during or immediately after a person's epileptic seizure or other seizure. [1] [2] When reliably trained such dogs can serve as service dogs for people with ...
A review in 2006 of the literature on use of benzodiazepine and nonbenzodiazepine hypnotics concluded that more research is needed to evaluate the long-term effects of hypnotic drugs. [84] The majority of the problems of benzodiazepines are related to their long-term use rather than their short-term use. [ 85 ]
Pagoclone is an anxiolytic agent from the cyclopyrrolone family, related to better-known drugs such as the sleeping medication zopiclone.It was synthesized by a French team working for Rhone-Poulenc & Rorer S.A. [1] Pagoclone belongs to the class of nonbenzodiazepines, which have similar effects to the older benzodiazepine group, but with quite different chemical structures.
Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States.Similar systems operate in other countries, but generally under different titles; for example, in Canada a typical title would be the University Animal Care Committee (UACC), while in the United Kingdom it would be the Animal Welfare and Ethical Review Body ...