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There are several ways to measure glycated hemoglobin, of which HbA1c (or simply A1c) is a standard single test. [5] HbA1c is measured primarily to determine the three-month average blood sugar level and is used as a standard diagnostic test for evaluating the risk of complications of diabetes and as an assessment of glycemic control .
[6] [7] [8] According to the American Diabetes Association, the fasting blood glucose target range for diabetics, should be 3.9 - 7.2 mmol/L (70 - 130 mg/dL) and less than 10 mmol/L (180 mg/dL) two hours after meals (as measured by a blood glucose monitor). [6] [7] [9] Normal value ranges may vary slightly between laboratories.
Beta cells are sensitive to blood sugar levels so that they secrete insulin into the blood in response to high level of glucose, and inhibit secretion of insulin when glucose levels are low. [10] Insulin production is also regulated by glucose: high glucose promotes insulin production while low glucose levels lead to lower production. [11]
A meta-analysis completed in 2007 and updated in 2020 of numerous randomized controlled trials by the international Cochrane Collaboration found that the effects on blood glucose and glycated haemoglobin A1c were comparable, treatment with glargine and detemir resulted in fewer cases of hypoglycemia when compared to NPH insulin. [24]
Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels during pregnancy. [2] Gestational diabetes generally results in few symptoms; [2] however, obesity increases the rate of pre-eclampsia, cesarean sections, and embryo macrosomia, as well as gestational diabetes. [2]
The aircraft travelling at low-level hit a one-storey house in the suburb of Souq Al-Jumaa in Tripoli killing the 2 crew and injuring two civilians. [268] 9 October A Fuerza Aérea Uruguaya EADS CASA C-212-200 Aviocar (FAU-531/UN-146) a twin-engined turboprop transport aircraft, on a reconnaissance flight crashed near Fonds-Verrettes, Ouest, Haiti.
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