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Myelopathy describes any neurologic deficit related to the spinal cord. [1] The most common form of myelopathy in humans, cervical spondylotic myelopathy (CSM) , [ 2 ] [ 3 ] also called degenerative cervical myelopathy , [ 4 ] results from narrowing of the spinal canal ( spinal stenosis ) ultimately causing compression of the spinal cord. [ 5 ]
Myelomalacia is a pathological term referring to the softening of the spinal cord. [1] Possible causes of myelomalacia include cervical myelopathy, hemorrhagic infarction, or acute injury, such as that caused by intervertebral disc extrusion.
Cervical canal stenosis may lead to myelopathy, a serious condition causing symptoms including major body weakness and paralysis. [14] Such severe spinal stenosis symptoms are virtually absent in lumbar stenosis , however, as the spinal cord terminates at the top end of the adult lumbar spine, with only nerve roots ( cauda equina ) continuing ...
Cervical Spondylotic Myelopathy (CSM) is a disorder characterised by the age-related deterioration of the cervical spinal cord. [1] Referred to be a range of different but related terms, a global consensus process selected Degenerative Cervical Myelopathy as the new overarching disease term . [ 2 ]
Mild myelopathy Increased deep tendon reflexes, sensory changes in lower extremities Adulthood Approximately 50% of women over 40 years of age Moderate to severe myeloneuropathy Similar to male AMN phenotype, but later onset and milder presentation Adulthood Approximately 15% of women over 40 years of age Cerebral involvement
Myelopathies such as tabes dorsalis (syphilitic myelopathy) Leukoencephalopathies such as progressive multifocal leukoencephalopathy; Leukodystrophies; The myelinoclastic disorders are typically associated with symptoms such as optic neuritis and transverse myelitis, because the demyelinating inflammation can affect the optic nerve or spinal cord.
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.
Myelopathy is an injury to the spinal cord due to severe compression that may result from trauma, congenital stenosis, degenerative disease or disc herniation. The spinal cord is a group of nerves housed inside the spine that runs almost its entire length.