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Guanfacine, sold under the brand name Tenex (immediate-release) and Intuniv (extended-release) among others, is an oral alpha-2a agonist medication used to treat attention deficit hyperactivity disorder (ADHD) and high blood pressure.
Attention deficit hyperactivity disorder management options are evidence-based practices with established treatment efficacy for ADHD.Approaches that have been evaluated in the management of ADHD symptoms include FDA-approved pharmacologic treatment and other pharmaceutical agents, psychological or behavioral approaches, combined pharmacological and behavioral approaches, cognitive training ...
Abilify (aripiprazole) – atypical antipsychotic used to treat schizophrenia, bipolar disorder, and irritability associated with autism; Adderall (mixed amphetamine salts) – a stimulant used to treat ADHD; Ambien – nonbenzodiazepine used as a sleep aid; Anafranil (clomipramine) – a tricyclic antidepressant; mostly used to treat OCD
[57] d-MPH has a similar side-effect profile to MPH [13] and can be administered without regard to food intake. [ 58 ] CTx-1301 is an experimental medication that is an extended-release formulation of dexmethylphenidate that has a half life more than an hour longer than extended-release dexmethylphenidate (d-MPH-ER).
Alpha2 adrenergic agonists can also be used to treat anxiety and panic, such as generalized anxiety disorder, panic disorder, or PTSD. Alpha2-adrenergic receptor agonists, such as clonidine and guanfacine , act at noradrenergic autoreceptors to inhibit the firing of cells in the locus ceruleus, effectively reducing the release of brain ...
Attention deficit hyperactivity disorder (ADHD) [1] is a neurodevelopmental disorder characterized by executive dysfunction occasioning symptoms of inattention, hyperactivity, impulsivity and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and developmentally-inappropriate.
This use of diphenhydramine has been criticized for a number of reasons, ranging from ethical to safety concerns, [25] but also due to the risk of diphenhydramine's paradoxical reaction, which induces hyperactivity and irritability. [26] This phenomenon can also be observed in adults who use the medication as a sleep aid.
Hypofrontality is a symptom of numerous neurological diseases defined as reduced utilization of glucose and blood flow in the prefrontal cortex. Hypofrontality can be difficult to detect under resting conditions, but under cognitive challenges, it has been seen to correlate with memory deficits along with executive function deficits.