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As haloperidol is a high-potency typical antipsychotic, it tends to produce significant extrapyramidal side effects. According to a 2013 meta-analysis of the comparative efficacy and tolerability of 15 antipsychotic drugs it was the most prone of the 15 for causing extrapyramidal side effects.
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine , benztropine , diphenhydramine , and ...
Haloperidol decanoate is provided in the form of 50 or 100 mg/mL oil solution of sesame oil and benzyl alcohol in ampoules or pre-filled syringes. [6] [7] [9] Its elimination half-life after multiple doses is 21 days. [10] [11] The medication is marketed in many countries throughout the world. [3] [12
If a scheduled injection of either haloperidol decanoate or fluphenazine decanoate is missed, recommendations for administering make-up injectable dose(s) or providing antipsychotics to be taken by mouth vary by, e.g., how long ago the last injection was and how many previous injections the person has received (i.e., if steady state levels of ...
Cosmetic injectables are on the rise and with them, telltale side effects like swelling, redness, and bruising. But the right post-injection skincare can help.
Side effects include muscle spasms and restlessness. Amisulpride (Barhemsys), administered by intravenous injection. Domperidone (Motilium) Droperidol; Olanzapine (Zyprexa) Haloperidol (limited in usefulness by extra-pyramidal and sedative side-effects) Alizapride; Prochlorperazine (Compazine, Stemzine, Buccastem, Stemetil, Phenotil)
Common side effects include movement problems, sleepiness, dry mouth, low blood pressure upon standing, and increased weight. [6] Serious side effects may include the potentially permanent movement disorder tardive dyskinesia , neuroleptic malignant syndrome , severe lowering of the seizure threshold , and low white blood cell levels . [ 6 ]
Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [ 1 ] [ 7 ] Symptoms include high fever , confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [ 1 ]