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Experts explain proven and new rescue therapies and migraine prevention protocols as well as which patients should and shouldn't try them.
Examples of specific antimigraine drug classes include triptans (first line option), ergot alkaloids, ditans and gepants. Migraines can also be treated with unspecific analgesics such as nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen. Opioids are not recommended for treatment of migraines.
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
They continued developing and working on a desirable action on 5-HT by 5-HT 1 receptor activation for an anti-migraine drug. Continued work led to the development of sumatriptan, now known as the first 5-HT 1 agonist, selective for the 5-HT 1D/B receptors and also the 5-HT 1F receptor with less affinity. By 1991 sumatriptan became available in ...
Academics said their findings are ‘important’ considering the higher costs of new treatments. New migraine drugs ‘comparable to paracetamol’, researchers suggest Skip to main content
New research from the United Kingdom finds that an older class of migraine drugs called triptans is often better than newer options when it comes to pain relief — they are also cheaper.
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