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The first MR images of a human brain were obtained in 1978 by two groups of researchers at EMI Laboratories led by Ian Robert Young and Hugh Clow. [1] In 1986, Charles L. Dumoulin and Howard R. Hart at General Electric developed MR angiography, [2] and Denis Le Bihan obtained the first images and later patented diffusion MRI. [3]
In addition to the long tracts that connect the brain to the rest of the body, there are complicated neural circuits formed by short connections among different cortical and subcortical regions. The existence of these tracts and circuits has been revealed by histochemistry and biological techniques on post-mortem specimens.
The paramedian pontine reticular formation (PMPRF) is involved in coordinating horizontal conjugate eye movements and saccades. To do so, besides projecting to the ibsilateral abducens nucleus, the PMPRF projects fibers through the MLF to the contralateral oculomotor nucleus (specifically, those of its motor neurons that innervate the medial rectus muscle).
The world record for the spatial resolution of a whole-brain MRI image was a 100-micrometer volume (image) achieved in 2019. The sample acquisition took about 100 hours. [ 2 ] The spatial world record of a whole human brain of any method was an X-ray tomography scan performing at the ESRF (European synchrotron radiation facility), which had a ...
The key to Phase-contrast MRI (PC-MRI) is the use of a bipolar gradient. [4] A bipolar gradient has equal positive and negative magnitudes that are applied for the same time duration. The bipolar gradient in PC-MRI is put in a sequence after RF excitation but before data collection during the echo time of the generic MRI modality.
Axial fluid-attenuated inversion recovery MRI image demonstrating tumor-related infiltration involving lenticular nuclei (Arrow). Axial fluid-attenuated inversion recovery MRI image demonstrating tumor-related infiltration involving both temporal lobes (Short arrow), and the substantia nigra (Long arrow).
The middle frontal gyrus makes up about one-third of the frontal lobe of the human brain. (A gyrus is one of the prominent "bumps" or "ridges" on the cerebral cortex.. The middle frontal gyrus, like the inferior frontal gyrus and the superior frontal gyrus, is more of a region in the frontal gyrus than a true gyrus.
Sagittal MRI slice with highlighting indicating location of the cingulate cortex. Coronal section of brain. Cingulate cortex is shown in yellow. The cingulate cortex is a part of the brain situated in the medial aspect of the cerebral cortex.