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Myocardial perfusion imaging or scanning (also referred to as MPI or MPS) is a nuclear medicine procedure that illustrates the function of the heart muscle (). [1]It evaluates many heart conditions, such as coronary artery disease (CAD), [2] hypertrophic cardiomyopathy and heart wall motion abnormalities.
Two primary stress tests utilized are a treadmill test using ECG/electrophysiology metrics and nuclear testing, each have unique sensitivity and specificity values. The treadmill test, employing the modified Bruce protocol , [ 20 ] demonstrates a sensitivity range of around 73-90% and a specificity range of around 50-74%.
In the second set, the patient is stressed either by exercising on a treadmill or pharmacologically. The drug is injected at peak stress and then imaging is performed. The resulting two sets of images are compared with each other to distinguish ischemic from infarcted areas of the myocardium. This imaging technique has a sensitivity of around ...
The modified Bruce Protocol is an alteration in the protocol so that the treadmill is initially horizontal rather than uphill, with the 1st few intervals increasing the treadmill slope only. [3] The Bruce treadmill test estimates maximum oxygen uptake using a formula and the performance of the subject on a treadmill as the workload is increased ...
Johns Hopkins cardiologists analyzed 58,000 heart stress tests to come up with an algorithm called the FIT Treadmill Score. The score factors in peak heart rate and metabolism. The score factors ...
However, if stress imaging is normal, it is unnecessary to perform rest imaging, as it too will be normal – thus stress imaging is normally performed first. MPI has been demonstrated to have an overall accuracy of about 83% ( sensitivity : 85%; specificity : 72%), [ 13 ] and is comparable (or better) than other non-invasive tests for ischemic ...
The underlying principle is, under conditions of stress, diseased myocardium receives less blood flow than normal myocardium. MPI is one of several types of cardiac stress test. As a nuclear stress test, the average radiation exposure is 9.4 mSv, which when compared with a typical 2 view chest X-ray (.1 mSv) is equivalent to 94 Chest X-rays. [83]
A cardiac stress test, puts stress on the heart through exercise. A series of exercises to measure the tolerance for stress on the heart will be carried out. This test uses an EKG to detect the electrical impulses of the heart during physical exertion. [29] A treadmill or exercise bike will be used.