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An enteric coating is a polymer barrier applied to oral medication that prevents its dissolution or disintegration in the gastric environment. [1] This helps by either protecting drugs from the acidity of the stomach, the stomach from the detrimental effects of the drug, or to release the drug after the stomach (usually in the upper tract of the intestine). [2]
Cellulose acetate phthalate (CAP), also known as cellacefate and cellulosi acetas phthalas, is a commonly used polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules and for controlled release formulations.
Phthalates can plasticise ethyl cellulose, polyvinyl acetate phthalate (PVAP) and cellulose acetate phthalate (CAP), all of which are used to make enteric coatings for tablet and capsule medications. These coatings protect drugs from the acidity of the stomach, but allow their release and absorption in the intestines.
Edwardsiella ictaluri (also known as enteric septicaemia of catfish, hole in the head disease [2] and ESC) is a member of the family Hafniaceae. The bacterium is a short, gram negative , pleomorphic rod with flagella.
Phthalic anhydride treated with cellulose acetate gives cellulose acetate phthalate (CAP), a common enteric coating excipient that has also been shown to have antiviral activity. [12] Phthalic anhydride is a degradation product of CAP. [13]
Microencapsulation is a process in which tiny particles or droplets are surrounded by a coating to give small capsules, with useful properties. [1] [2] In general, it is used to incorporate food ingredients, [3] enzymes, cells or other materials on a micro metric scale.
Copolymers consisting partially of methacrylic acid are used in certain types of tablet coatings in order to slow the tablet's dissolution in the digestive tract, and thus extend or delay the release of the active ingredient. [8] MAA occurs naturally in small amounts in the oil of Roman chamomile. [citation needed]
Shellac dissolved in alcohol, typically more dilute than as used in French polish, is now commonly sold as "sanding sealer" by several companies. It is used to seal wooden surfaces, often as preparation for a final more durable finish; it reduces the amount of final coating required by reducing its absorption into the wood. [citation needed]