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  2. Hepatic portal system - Wikipedia

    en.wikipedia.org/wiki/Hepatic_portal_system

    The inferior mesenteric vein connects in the majority of people on the splenic vein, but in some people, it is known to connect on the portal vein or the superior mesenteric vein. Roughly, the portal venous system corresponds to areas supplied by the celiac trunk , the superior mesenteric artery , and the inferior mesenteric artery .

  3. Portal venous system - Wikipedia

    en.wikipedia.org/wiki/Portal_venous_system

    The human hepatic portal system delivers about three-fourths of the blood going to the liver.The final common pathway for transport of venous blood from spleen, pancreas, gallbladder and the abdominal portion of the gastrointestinal tract [2] (with the exception of the inferior part of the anal canal and sigmoid colon) is through the hepatic portal vein.

  4. Portal vein - Wikipedia

    en.wikipedia.org/wiki/Portal_vein

    It is a major component of the hepatic portal system, one of three portal venous systems in the human body; the others being the hypophyseal and renal portal systems. The portal vein is usually formed by the confluence of the superior mesenteric , splenic veins , inferior mesenteric , left , right gastric veins and the pancreatic vein .

  5. Lobules of liver - Wikipedia

    en.wikipedia.org/wiki/Lobules_of_liver

    In histology (microscopic anatomy), the lobules of liver, or hepatic lobules, are small divisions of the liver defined at the microscopic scale. The hepatic lobule is a building block of the liver tissue, consisting of a portal triad, hepatocytes arranged in linear cords between a capillary network, and a central vein.

  6. Portacaval anastomosis - Wikipedia

    en.wikipedia.org/wiki/Portacaval_anastomosis

    A portacaval anastomosis or portocaval anastomosis is a specific type of circulatory anastomosis that occurs between the veins of the portal circulation and the vena cava, thus forming one of the principal types of portasystemic anastomosis or portosystemic anastomosis, as it connects the portal circulation to the systemic circulation, providing an alternative pathway for the blood.

  7. Splenic vein - Wikipedia

    en.wikipedia.org/wiki/Splenic_vein

    The splenic vein is formed from small venules that leave the spleen. It travels above the pancreas, alongside the splenic artery.It collects branches from the stomach and pancreas, and most notably from the large intestine (also drained by the superior mesenteric vein) via the inferior mesenteric vein, which drains in the splenic vein shortly before the origin of the hepatic portal vein.

  8. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    Illustration showing the hepatic portal vein system. The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

  9. Cardiovascular physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiovascular_physiology

    Blood flow through the left coronary artery is at a maximum during diastole (in contrast to the rest of systemic circulation, which has a maximum blood flow during systole.) splanchnic circulation: 15%: low: Flow increases during digestion. hepatic circulation: 15%: Part of portal venous system, so oncotic pressure is very low renal circulation ...