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Particularly, damage to hippocampal CA1 cells adversely affects memory formation, [3] and this disruption has been linked to dose-dependent levels of alcohol consumption. [4] At higher doses, alcohol significantly inhibits neuronal activity in both the CA1 and CA3 pyramidal cell layers of the hippocampus.
Alcohol-related brain damage [1] [2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe , [ 3 ] limbic system , and cerebellum , [ 4 ] with widespread ...
PTSD can affect several parts of the brain such as the amygdala, hippocampus, and the prefrontal cortex. The amygdala controls our memory and emotional processing; the hippocampus helps with organizing, storing and memory forming. Hippocampus is the most sensitive area to stress. [59]
Damage to different areas of the brain can have varied effects on memory. The temporal lobes, on the sides of the brain, contain the hippocampus and amygdala, and therefore have a lot to do with memory transition and formation. Patients who have had injury to this area have experienced problems creating new long-term memories.
Brain plasticity has helped explain the recovery process of brain damage induced retrograde amnesia, where neuro-structures use different neural pathways to avoid the damaged areas while still performing their tasks. [42] Thus, the brain can learn to be independent of the impaired hippocampus, but only to a certain extent. [13]
Damage to any part of this system, including the hippocampus and surrounding cortices, results in amnesic syndromes. [1] This is why after a stroke people have a chance of developing cognitive deficits that result in anterograde amnesia, since strokes can involve the temporal lobe in the temporal cortex, and the temporal cortex houses the ...
The hippocampus (pl.: hippocampi; via Latin from Greek ἱππόκαμπος, 'seahorse'), also hippocampus proper, is a major component of the brain of humans and many other vertebrates. In the human brain the hippocampus, the dentate gyrus, and the subiculum are the components of the hippocampal formation located in the limbic system.
Damage to the right parietal lobe can result in neglecting part of the body or space (contralateral neglect), which can impair many self-care skills such as dressing and washing. Right side damage can also cause difficulty in making things (constructional apraxia ), denial of deficits ( anosognosia ) and drawing ability. [ 21 ]