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CGRP can also release inflammatory agents and cause nervous system sensitization. [14] It is theorized that by antagonizing the CGRP receptor of the trigeminal ganglia, lowered CGRP is released and less migraine occurs. [14] Erenumab is a highly selective human monoclonal antibody which is a promising new development in migraine treatment. [14]
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
Migraine (UK: / ˈ m iː ɡ r eɪ n /, US: / ˈ m aɪ-/) [1] [2] is a genetically-influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity.
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Primary headaches are benign, recurrent headaches not caused by underlying disease or structural problems. For example, migraine is a type of primary headache. While primary headaches may cause significant daily pain and disability, they are not dangerous from a physiological point of view.
A migraine cap, also known as a migraine mask, headache hat or an ice cap, is a wearable sleeve designed to wrap around the head to provide relief from resulting headaches.
In the absence of evidence-based indications, in MOH patients the choice of preventive agent should be based on the primary headache type (migraine or TTH), on the drug side-effect profile, on the presence of co-morbid and co-existent conditions, on patient's preferences, and on previous therapeutic experiences. [30]
Some migraine medicationswork by increasing dopamine levels, which can help ease migraine symptoms. On the flip side, consuming aspartame may cause dopamine levels to dip, potentially leading to a ...