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Acetic acid has been used medically since the time of Ancient Egypt. [8] [9] It is on the World Health Organization's List of Essential Medicines. [10] Acetic acid is more commonly used for external ear infections in the developing world than the developed. [11]
Burow's solution is an aqueous solution of aluminium triacetate.It is available in the U.S. as an over-the-counter drug for topical administration, with brand names including Domeboro (Moberg Pharma), Domeboro Otic (ear drops), Star-Otic, and Borofair. [1]
Acetic acid/hydrocortisone is a commonly used combination drug to treat infections of the outer ear and ear canal. Branded as Vosol HC and Acetasol HC , it combines the antibacterial and antifungal action of acetic acid with the anti-inflammatory functions of hydrocortisone .
Ear drops should not be shared to prevent the spread of infection. [7] Ear drops should not be used after the expiration date. [7] Ear drops should only be used in the affected ear. Ear drops are usually used for a short duration of time. Make sure to only use it as prescribed. [7]
When the ear canal skin is inflamed from the acute otitis externa, the use of dilute acetic acid may be painful. Burow's solution is a very effective remedy against both bacterial and fungal external otitis. This is a buffered mixture of aluminium sulfate and acetic acid, and is available without prescription in the United States. [21]
The average middle ear volume is 0.4 mL, which limits otic accumulation in overdose. [6] It is unlikely that an cerumenolytic administered into the ear would cause systemic toxicity in an overdose situation, due to the lack of systemic absorption resulting from minimal volume flow within the inner ear. [7]