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Obesity hypoventilation syndrome is defined as the combination of obesity and an increased blood carbon dioxide level during the day that is not attributable to another cause of excessively slow or shallow breathing. [2] The most effective treatment is weight loss, but this may require bariatric surgery to achieve. [3]
The term "Pickwickian syndrome" that is sometimes used for the syndrome was coined by the famous early 20th-century physician William Osler, who must have been a reader of Charles Dickens. The description of Joe, "the fat boy" in Dickens's novel The Pickwick Papers , is an accurate clinical picture of an adult with obstructive sleep apnea syndrome.
Pickwickian syndrome, a medical disease named from the Dickens novel Don Pickwick (1925–2004), Welsh footballer Eleazer Pickwick (1748 or 1749–1837), British businessman
Symptoms of Peyronie’s Disease. The most apparent symptom of Peyronie’s disease is a deformity of the aroused privates, which can be a new curvature of the privates or a focal loss of aroused ...
As a side effect of medicines or recreational drugs, hypoventilation may become potentially life-threatening.Many different central nervous system (CNS) depressant drugs such as ethanol, benzodiazepines, barbiturates, GHB, sedatives, and opioids produce respiratory depression when taken in large or excessive doses, or mixed with other depressants.
Insomnias were classified as primary and secondary until 1970 when they were recognized as symptoms of other disorders. Sir William Osler in 1906 correlated snoring, obesity and somnolence (sleepiness) to Dicken's description of Joe. Charles Burwell in 1956 recognized obstructive sleep apnea as Pickwickian syndrome. [6]
Its symptoms can come and go. Periods when gout symptoms are more severe are called gout flares or gout attacks. A gout flare comes on suddenly, and symptoms are often intense.
Individuals with PKS present prenatally or at birth with multiple birth defects.These defects include: brain atrophy, agenesis of the corpus callosum, polymicrogyria of the brain, and/or spot calcifications in the brain's lateral sulcus; deafness and/or blindness; autonomic nervous system dysfunctions such as anhidrosis, hypohidrosis, and/or episodic spells of hyperventilation interspersed ...