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Stevens–Johnson syndrome (SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease , with SJS being less severe.
This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
At 8 years old, Paige LaCombe was diagnosed with a rare and life-threatening skin disease called Stevens-Johnson syndrome. The now 19-year-old recalls her yearslong recovery journey at Shriners ...
Stevens-Johnson/toxic epidermal necrolysis overlap syndrome (SJS/TEN); and Acute generalized exanthematous pustulosis (AGEP). The five disorders have similar pathophysiologies , i.e. disease-causing mechanisms, for which new strategies are in use or development to identify individuals predisposed to develop the SCARs-inducing effects of ...
Studies on the DRESS syndrome, Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS/TEN overlap indicate that many individuals are predisposed to develop these reactions to a particular medication based on their genetically determined expression of particular human leukocyte antigen (i.e. HLA) alleles or T-cell receptors ...
Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a type of severe skin reaction. [2] Together with Stevens–Johnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. [2] Early symptoms include fever and flu-like symptoms. [2] A few days later the skin begins to blister and peel forming painful raw ...
Family tensions reach a head when the children realize the holiday is not going to happen and a foreclosure notice is posted on the house. Robbie's epilepsy gets worse, and he develops a serious rash known as Stevens–Johnson syndrome as a side effect of the medication. He is admitted to the hospital where his padded cot is designed to prevent ...
Severe side effects may include suicide and psychosis. [ 8 ] [ 7 ] Use during pregnancy may result in harm to the fetus. [ 9 ] Primidone is an anticonvulsant of the barbiturate class; [ 7 ] however, its long-term effect in raising the seizure threshold is likely due to its active metabolite, phenobarbital . [ 10 ]