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  2. Sudam Kate - Wikipedia

    en.wikipedia.org/wiki/Sudam_Kate

    Dr. Sudam Kate is an Indian social activist doctor known for his pioneering work in the field of Sickle-Cell Anaemia in India. Working with Maharashtra Arogya Mandal, Hadapsar, Pune; he helped diagnose and later treated over 3000 sickle cell patients from the rural tribal communities of Maharashtra, Gujarat and Madhya Pradesh, working since 1972.

  3. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...

  4. Human genetic resistance to malaria - Wikipedia

    en.wikipedia.org/wiki/Human_genetic_resistance...

    Sickle-cell disease was the genetic disorder to be linked to a mutation of a specific protein. Pauling introduced his fundamentally important concept of sickle cell anemia as a genetically transmitted molecular disease. [20] This vein (4) shows the interaction between the malaria sporozoites (6) with sickle cells (3) and regular cells (1).

  5. Sickle Cell Anemia, a Molecular Disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a...

    Sickle Cell Anemia, a Molecular Disease. " Sickle Cell Anemia, a Molecular Disease " is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.

  6. Elizabeth Anionwu - Wikipedia

    en.wikipedia.org/wiki/Elizabeth_Anionwu

    Website. www.elizabethanionwu.co.uk. Dame Elizabeth Nneka Anionwu OM DBE FRCN (born Elizabeth Mary Furlong; 2 July 1947) is a British nurse, health care administrator, lecturer, and Emeritus Professor of Nursing at the University of West London. In 1979, Anionwu became the United Kingdom's first sickle-cell and thalassemia nurse specialist ...

  7. Yvette Francis-McBarnette - Wikipedia

    en.wikipedia.org/wiki/Yvette_Francis-McBarnette

    Occupation (s) Pediatrician, Haematologist. Known for. Pioneer in the treatment of the sickle cell anaemia. Spouse. Olvin R. McBarnette. Parent (s) Clarence and Sarah Francis. Yvette Francis-McBarnette (May 10, 1926 – March 28, 2016) was an American pediatrician and a pioneer in treating children with sickle cell anaemia.

  8. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    Sickle-cell anemia (SCA) is a genetic disorder caused by the presence of two incompletely recessive alleles. When a sufferer's red blood cells are exposed to low-oxygen conditions, the cells lose their healthy round shape and become sickle-shaped. This deformation of the cells can cause them to become lodged in capillaries, depriving other ...

  9. Anthony Clifford Allison - Wikipedia

    en.wikipedia.org/wiki/Anthony_Clifford_Allison

    Anthony Clifford Allison (21 August 1925 – 20 February 2014) was a South African geneticist and medical scientist who made pioneering studies on the genetic resistance to malaria. [2] Clark completed his primary schooling in Kenya, completed his higher education in South Africa, and obtained a BSc in medical science from the University of the ...