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It is available in the form of an inhaler containing 50 mg total per inhaler and delivering between 0.04 and 0.15 mg of the drug per inhalation. [2] Inhalers with a total of 113 mg levmetamfetamine were previously marketed in the United States, but the total amount was eventually reduced to 50 mg. [2]
[10] [5] The drug is known to increase wakefulness and concentration in association with decreased appetite and fatigue. [ 11 ] [ 12 ] Pharmaceuticals that contain levoamphetamine are currently indicated and prescribed for the treatment of attention deficit hyperactivity disorder (ADHD), obesity , and narcolepsy in some countries.
To avoid toxicity and risk of side effects, FDA guidelines recommend an initial dose of methamphetamine at doses 5–10 mg/day for ADHD in adults and children over six years of age, and may be increased at weekly intervals of 5 mg, up to 25 mg/day, until optimum clinical response is found; the usual effective dose is around 20–25 mg/day.
Amphetamine is a weak base with a pK a of 9.9; [3] consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid-rich cell membranes of the gut epithelium. [3] [29] Conversely, an acidic pH means the drug is predominantly in a water-soluble cationic (salt) form, and less is ...
Of course, reviewers have found other uses for these inhaler sticks outside of cold- and flu-season, too. "One quick sniff and you are able to breathe again," wrote one reviewer who carries the ...
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Vicks is an American brand of over-the-counter medications owned by the American companies Procter & Gamble and Kaz Incorporated. Vicks manufactures NyQuil and its sister medication, DayQuil as well as other medications in the "Quil" line.
The manufacture of propylhexedrine products for therapeutic use is typically performed based on guidelines established in government regulations and pharmacopeia monographs. [ 42 ] [ 5 ] The illicit manufacture or diversion of propylhexedrine by clandestine chemists for use as a recreational drug has been documented in academic literature. [ 35 ]