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  2. HPA-23 - Wikipedia

    en.wikipedia.org/wiki/HPA-23

    HPA-23 was developed by Rhône-Poulenc at the Pasteur Institute in the 1970s and used in France on an experimental basis to treat HIV and AIDS patients beginning in 1984. [1] [2] The inventors of the drug, as listed in its patent, were Jean-Claude Chermann, Dominique Dormont, Etienne Vilmer, Bruno Spire, Françoise Barré-Sinoussi, Luc Montagnier, and Willy Rozenbaum. [3]

  3. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

  4. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  5. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain . [ 2 ]

  6. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    When used as drugs, the International Nonproprietary Names (INNs) end in -mab. The remaining syllables of the INNs, as well as the column Source, are explained in Nomenclature of monoclonal antibodies. Types of monoclonal antibodies with other structures than naturally occurring antibodies.

  7. HIV isn't the death sentence it once was: How related deaths ...

    www.aol.com/hiv-isnt-death-sentence-once...

    Nearly 2 in 3 Americans diagnosed with HIV have reached viral suppression, though the lowest rates are among women, those aged 25 to 34, Black people, and people who inject drugs, Fanfair said.

  8. Fondaparinux - Wikipedia

    en.wikipedia.org/wiki/Fondaparinux

    Fondaparinux is a synthetic pentasaccharide factor Xa inhibitor. Fondaparinux binds antithrombin and accelerates its inhibition of factor Xa.. Apart from the O-methyl group at the reducing end of the molecule, the identity and sequence of the five monomeric sugar units contained in fondaparinux is identical to a sequence of five monomeric sugar units that can be isolated after either chemical ...

  9. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    Warfarin should not be given to people with heparin-induced thrombocytopenia until platelet count has improved or normalised. [39] Warfarin is usually best avoided in people with protein C or protein S deficiency, as these thrombophilic conditions increase the risk of skin necrosis, which is a rare but serious side effect associated with ...