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Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis, Hashimoto's disease and autoimmune thyroiditis, is an autoimmune disease in which the thyroid gland is gradually destroyed. [7] [1] Early on, symptoms may not be noticed. [3] Over time, the thyroid may enlarge, forming a painless goiter. [3]
Thyroid gland: TSI, TPO, TG antibodies Confirmed 1.2% of the population [80] Hashimoto's thyroiditis: Thyroid gland: TPO, TG antibodies Confirmed 5% of the population [81] Ord's thyroiditis: Thyroid gland: TPO, TG antibodies Confirmed Rare [82] Sjögren syndrome: Exocrine glands (salivary and lacrimal glands) Anti-SSA/Ro, Anti-SSB/La antibodies ...
Hashimoto's encephalopathy, also known as steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), is a neurological condition characterized by encephalopathy, thyroid autoimmunity, and good clinical response to corticosteroids. It is associated with Hashimoto's thyroiditis, and was first
Thyroiditis is generally caused by an immune system attack on the thyroid, resulting in inflammation and damage to the thyroid cells. This disease is often considered a malfunction of the immune system and can be associated with IgG4-related systemic disease, in which symptoms of autoimmune pancreatitis, retroperitoneal fibrosis and noninfectious aortitis also occur.
Hashitoxicosis, which can be abbreviated "Htx", [1] is a transient hyperthyroidism caused by inflammation associated with Hashimoto's thyroiditis disturbing the thyroid follicles, resulting in excess release of thyroid hormone. [2
Although there is overlap, anti-TPO antibodies are most commonly associated with Hashimoto's thyroiditis and activating TRAb's are most commonly associated with Graves' disease. Thyroid microsomal antibodies were a group of anti-thyroid antibodies; they were renamed after the identification of their target antigen (TPO). [1] [2] [3] [4]
Over time, thyroid damage can cause thyroid hormone levels to be too low. This is called an underactive thyroid or hypothyroidism (heye-poh-THEYE-royd-ism). An underactive thyroid causes every function of the body to slow down, such as heart rate, brain function, and the rate your body turns food into energy.
Hakaru Hashimoto (橋本 策, Hashimoto Hakaru, May 5, 1881 – January 9, 1934) [1] [2] was a Japanese doctor and medical scientist of the Meiji and Taishō periods. He is best known for publishing the first description of the disease that was later named Hashimoto's thyroiditis .