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Budesonide, sold under the brand name Pulmicort, among others, is a steroid medication. [8] It is available as an inhaler , nebulization solution , pill , nasal spray , and rectal forms . [ 8 ] [ 9 ] The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD).
Steroid enemas can be used for treatment of rectal disease symptoms. Corticosteroids are a class of anti-inflammatory drugs used to treat moderate to severe flares of Crohn's disease. However, they are used sparingly because they can cause serious side effects, [ 4 ] including Cushing's syndrome , mania , insomnia , hypertension , high blood ...
Addison's disease, also known as primary adrenal insufficiency, [4] is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency.
Cortisone = 17α,21-dihydroxypregn-4-ene-3,11,20-trione; Pregnenolone = pregn-5-en-3β-ol-20-one; Progesterone = pregn-4-ene-3,20-dione; The glucocorticoid activity of progesterone and 17α-hydroxyprogesterone is very weak (>100-fold less than that of cortisol). [1] The above list includes precursors and intermediates in corticosteroid ...
Abrupt termination of the drug commonly causes transient non-specific symptoms such as loss of appetite, upset stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss. [29] [30] These symptoms can be attributed to steroid withdrawal syndrome, adrenal insufficiency, or disease relapse. [29]
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...