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Radium (usually in the form of radium chloride or radium bromide) was used in medicine to produce radon gas, which in turn was used as a cancer treatment. [6] Several of these radon sources were used in Canada in the 1920s and 1930s. [62]
Radithor was a patent medicine that is a well-known example of radioactive quackery. It consisted of triple-distilled water containing at a minimum 1 microcurie (37 kBq) each of the radium-226 and 228 isotopes.
RNT contrasts with sealed-source therapy (brachytherapy) where the radionuclide remains in a capsule or metal wire during treatment and needs to be physically placed precisely at the treatment position. [4] When the radionuclides are ligands (such as with Lutathera and Pluvicto), the technique is also known as radioligand therapy. [5]
Many years ago radium-226 and radon-222 were used as gamma-ray sources for industrial radiography: for instance, a radon-222 source was used to examine the mechanisms inside an unexploded V-1 flying bomb, while some of the early Bathyspheres could be examined using radium-226 to check for cracks.
Tho-Radia, a cream containing radium bromide, notable for its iconic advertising using the name of Dr. Alfred Curie, who shared the surname of Pierre and Marie Curie but had no connection to them. Radithor, a solution of radium salts, which was claimed by its developer William J. A. Bailey to have curative properties.
Radium was soon seen as a way to treat disorders that were not affected enough by x-ray treatment because it could be applied in a multitude of ways in which x-rays could not. [15] Different methods of applying radium had been tested, which fell into two categories: the use of radium emanation (now referred to as radon), and the use of radium ...
Through the 1920s the hazards of radiation exposure were not understood, and little protection was used. Radium was believed to have wide curative powers and radiotherapy was applied to many diseases. Prior to World War 2, the only practical sources of radiation for radiotherapy were radium, its "emanation", radon gas, and the X-ray tube.
Radium-223 dichloride (USP, radium chloride Ra 223), tradename Xofigo (formerly Alpharadin), is an alpha-emitting radiopharmaceutical. Bayer received FDA approval for this drug to treat prostate cancer osteoblastic bone metastases in May 2013. Radium-223 chloride is one of the most potent ((antineoplastic drugs)) known.