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Chondrification (also known as chondrogenesis) is the process by which cartilage is formed from condensed mesenchyme tissue, [2] which differentiates into chondrocytes and begins secreting the molecules that form the extracellular matrix. Early in fetal development, the greater part of the skeleton is cartilaginous.
In embryogenesis, the skeletal system is derived from the mesoderm germ layer. Chondrification (also known as chondrogenesis) is the process by which cartilage is formed from condensed mesenchyme tissue, which differentiates into chondroblasts and begins secreting the molecules (aggrecan and collagen type II) that form the extracellular matrix.
Corns from an acute injury, such as from a thorn in the sole of the foot, may form due to the weight of the body, when the process that creates the usually evenly developing plantar callus is concentrated at the point of the healing injury, as an internal callus may be triggered by pressure on the transitional scar tissue. Once formed, the corn ...
The foot may is a complex structure with 26 bones, 33 joints, numerous muscles, nerves and different ligament types. Any part of the foot can be affected by diseases, with symptoms ranging from mild aches to more serious pain hindering one's ability to walk or bear weight. Most minor cases of foot pain can be responded to by home care treatments.
When referring to bone, or in this case cartilage, the originally undifferentiated mesenchymal stem cells lose their pluripotency, proliferate and crowd together in a dense aggregate of chondrogenic cells (cartilage) at the location of chondrification. These chondrogenic cells differentiate into so-called chondroblasts, which then synthesize ...
Eumycetoma, also known as Madura foot, [1] [6] is a persistent fungal infection of the skin and the tissues just under the skin, affecting most commonly the feet, although it can occur in hands and other body parts. [5]
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The affected foot tends to have a sclerotic and flattened navicular bone. Symptoms may last for a few weeks or may continue to be present for up to 2 years. [ 4 ] An indication of the symptoms residing is the resolution of the acute inflammation and obvious healing of the foot.