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Imidazole is a planar 5-membered ring, that exists in two equivalent tautomeric forms because hydrogen can be bound to one or another nitrogen atom. Imidazole is a highly polar compound, as evidenced by its electric dipole moment of 3.67 D, [12] and is highly soluble in water.
2-Imidazoline (Preferred IUPAC name: 4,5-dihydro-1H-imidazole) is one of three isomers of the nitrogen-containing heterocycle imidazoline, with the formula C 3 H 6 N 2.The 2-imidazolines are the most common imidazolines commercially, as the ring exists in some natural products and some pharmaceuticals.
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In nature, imidazole alkaloids are found both as secondary plant compounds and as byproducts of histidine metabolism in marine organisms. One well-known imidazole alkaloid is pilocarpine , which is present in the leaves of Paraguay jaborandi .
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2) is the conjugate base of imidazole. It is a nucleophile and a strong base. The free anion has C 2v symmetry. Imidazole has a pK a of 14.05, [1] so the deprotonation of imidazole (C 3 H 3 N 2 H) requires a strong base.
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Imidazothiazoles are a class of chemical compounds containing a bicyclic heterocycle (a double ring system) consisting of an imidazole ring fused to a thiazole ring. [1] The structure contains three non- carbon or heteroatoms : two nitrogen atoms and one sulfur atom.