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Downstream processing and analytical bioseparation both refer to the separation or purification of biological products, but at different scales of operation and for different purposes. Downstream processing implies manufacture of a purified product fit for a specific use, generally in marketable quantities, while analytical bioseparation refers ...
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At reduced pressure, distillation of product directly from fermentor may be possible. The steps of downstream processing are: Separation of biomass: separating the biomass (microbial cells) generally carried out by centrifugation or ultra-centrifugation. If the product is biomass, then it is recovered for processing and spent medium is discarded.
High G+C Gram-positive bacteria Bacillati "Bipolaricaulota" Hao et al. 2018 KB1 "Acetothermia" (OP1) "Fraserbacteria" (RIF31) Bacillati: Deinococcota: Weisburg, Giovannoni & Woes 2021 Bacillati "Margulisiibacteriota" corrig. Anantharaman et al. 2016 "Saganbacteria" Bacillati: Cyanobacteriota: Oren, Mares & Rippka 2022 Blue-green algae ...
Protein precipitation is widely used in downstream processing of biological products in order to concentrate proteins and purify them from various contaminants. For example, in the biotechnology industry protein precipitation is used to eliminate contaminants commonly contained in blood. [1]
Microbial food cultures are live bacteria, yeasts or moulds used in food production. Microbial food cultures carry out the fermentation process in foodstuffs. Used by humans since the Neolithic period (around 10 000 years BC) [1] fermentation helps to preserve perishable foods and to improve their nutritional and organoleptic qualities (in this case, taste, sight, smell, touch).