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Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
Servier states that the use is now restricted to treatment of severe osteoporosis in postmenopausal women at high risk for fracture. [2] The European Pharmacovigilance Risk Assessment Committee (PRAC) recommended restriction in the use of strontium ranelate, based on a routine benefit-risk assessment of the medicine, which included data showing ...
Bisphosphonates are used to treat osteoporosis, osteitis deformans (Paget's disease of the bone), bone metastasis (with or without hypercalcemia), multiple myeloma, and other conditions involving fragile, breakable bone. In osteoporosis and Paget's, the most popular first-line bisphosphonate drugs are alendronate and risedronate.
It is an effective anabolic (promoting bone formation) agent [15] used in the treatment of some forms of osteoporosis. [13] [16] Teriparatide is a recombinant human parathyroid hormone analog (PTH 1-34). [13] It has an identical sequence to the 34 N-terminal amino acids of the 84-amino acid human parathyroid hormone. [13]
Steps that older adults can take to reduce their risk of falls and fractures include getting screened for osteoporosis, especially for women 65 and older, Rao said, and getting regular exercise.
Primary, or involuntary osteoporosis, can further be classified into Type I or Type II. [1] Type I refers to postmenopausal osteoporosis and is caused by the deficiency of estrogen. [1] While senile osteoporosis is categorized as an involuntary, Type II, and primary osteoporosis, which affects both men and women over the age of 70 years.