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  2. Lacunar stroke - Wikipedia

    en.wikipedia.org/wiki/Lacunar_stroke

    Pure motor stroke/hemiparesis (most common lacunar syndrome: 33–50%) posterior limb of the internal capsule , basilar part of pons , corona radiata It is marked by hemiparesis or hemiplegia that typically affects the face, arm, or leg of the side of the body opposite the location of the infarct.

  3. Lentiform nucleus - Wikipedia

    en.wikipedia.org/wiki/Lentiform_nucleus

    The lentiform nucleus (or lentiform complex, lenticular nucleus, or lenticular complex) are the putamen (laterally) and the globus pallidus (medially), collectively. Due to their proximity, these two structures were formerly considered one, however, the two are separated by a thin layer of white matter—the external medullary lamina—and are functionally and connectionally distinct.

  4. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  5. Striatum - Wikipedia

    en.wikipedia.org/wiki/Striatum

    The striatum (pl.: striata) or corpus striatum [5] is a cluster of interconnected nuclei that make up the largest structure of the subcortical basal ganglia. [6] The striatum is a critical component of the motor and reward systems; receives glutamatergic and dopaminergic inputs from different sources; and serves as the primary input to the rest of the basal ganglia.

  6. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Treatment of people aged twelve years of age and older with solid tumors that: have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion, are locally advanced or metastatic or where surgical resection is likely to result in severe morbidity, and have progressed following treatment or have no satisfactory alternative therapy [2]

  7. Basal ganglia - Wikipedia

    en.wikipedia.org/wiki/Basal_ganglia

    The subthalamic nucleus is a diencephalic gray matter portion of the basal ganglia, and the only portion of the ganglia that produces an excitatory neurotransmitter, glutamate. The role of the subthalamic nucleus is to stimulate the SNr-GPi complex and it is part of the indirect pathway. The subthalamic nucleus receives inhibitory input from ...

  8. Putamen - Wikipedia

    en.wikipedia.org/wiki/Putamen

    The putamen (/ p j u ˈ t eɪ m ə n /; from Latin, meaning "nutshell") is a subcortical nucleus with a rounded structure, in the basal ganglia nuclear group. It is located at the base of the forebrain and above the midbrain. The putamen and caudate nucleus together form the dorsal striatum.

  9. Primary familial brain calcification - Wikipedia

    en.wikipedia.org/wiki/Primary_familial_brain...

    Primary familial brain calcification [1] (PFBC), also known as familial idiopathic basal ganglia calcification (FIBGC) and Fahr's disease, [1] is a rare, [2] genetically dominant or recessive, inherited neurological disorder characterized by abnormal deposits of calcium in areas of the brain that control movement.