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Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy ...
Nevus depigmentosus is a loss of pigment in the skin which can be easily differentiated from vitiligo. Although age factor has not much involvement in the nevus depigmentosus but in about 19% of the cases these are noted at birth. Their size may however grow in proportion to growth of the body.
[5] [6] [7] The epidermis is the most superficial layer of skin, a squamous epithelium with several strata: the stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale. [8] Nourishment is provided to these layers by diffusion from the dermis since the epidermis is without direct blood supply.
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Vitiligo, meanwhile, is a disorder that takes place when pigment-producing cells stop functioning. Winnie Harlow and the late Michael Jackson are some of the celebrities who have spoken out about ...
Childhood Mycosis fungoides makes up 0.5% to 7.0% of cases. [14] Although data on childhood MF is limited, a 2021 systematic review observed that there is a significant delay in the diagnosis of childhood MF which may negatively affect a child's prognosis. Notably, most pediatric persons with MF present with early-stage disease. [14]
EDSS steps 5.0 to 9.5 are defined by the impairment to ambulation. The clinical meaning of each possible result is the following: 0.0: Normal Neurological Exam; 1.0: No disability, minimal signs in 1 FS; 1.5: No disability, minimal signs in more than 1 FS; 2.0: Minimal disability in 1 FS; 2.5: Mild disability in 1 or Minimal disability in 2 FS
Deafness-vitiligo-achalasia syndrome is an extremely rare genetic disorder characterized by congenital hearing loss, vitiligo, low height, muscle degeneration and achalasia. [ 1 ] [ 2 ] It was first discovered in 1971, when Rozycki et al., when they described two siblings of the opposite sex with the symptoms mentioned above.