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The disease was once thought to be a lipid storage disease as the lesions have a high cholesterol content, but the blood cholesterol is usually normal. [ 5 ] [ 13 ] Some sources such as the National Cancer Institute describe it as a type of cancer , [ 14 ] while other sources specifically state it is not a type of cancer.
With multi-focal disease 60% have a chronic course, 30% achieve remission and mortality is up to 10%. [48] A full recovery can be expected for people who seek treatment and do not have more lesions at 12 and 24 months. However, 50% of children under 2 with disseminated Langerhans cell histiocytosis die of the disease.
In hematology, plasma cell dyscrasias (also termed plasma cell disorders and plasma cell proliferative diseases) are a spectrum of progressively more severe monoclonal gammopathies in which a clone or multiple clones of pre-malignant or malignant plasma cells (sometimes in association with lymphoplasmacytoid cells or B lymphocytes) over-produce and secrete into the blood stream a myeloma ...
Imiquimod (Aldara) has been used with success for squamous-cell carcinoma in situ of the skin and the penis, but the morbidity and discomfort of the treatment is severe. An advantage is the cosmetic result: after treatment, the skin resembles normal skin without the usual scarring and morbidity associated with standard excision.
Stage 2 symptoms happen next, and may include:. Rashes on other parts of your body. A stiff or painful neck. Muscle weakness on one or both sides of your face. Irregular heartbeat
At least one case of FIP1L1-PDGFRA fusion gene-induced eosinophilic leukemia presenting with myeloid sarcoma and eosinophilia has been reported. This form of myeloid sarcoma is distinguished by its highly successful treatment with imatinib (the recommended treatment for FIP1L1-PDGRGA fusion gene-induced eosinophilic leukemia) rather than more aggressive and toxic therapy.
Melissa Gilbert opened up about the “brutal and pernicious” disease that took Michael Landon and Patrick Swayze’s lives. She’s raising awareness for pancreatic cancer through her lifestyle ...
Dave Coulier has had some "tough days" since being diagnosed with cancer last fall, but he's determined to "power through.". The actor's wife, Melissa Coulier, opened up about his ongoing battle ...