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Actinomycosis is a rare infectious bacterial disease caused by the gram-positive Actinomyces species. [1] The name refers to ray-like appearance of the organisms in the granules. About 70% of infections are due to either Actinomyces israelii or A. gerencseriae. [1] Infection can also be caused by Streptomyces somaliensis and Propionibacterium ...
Actinomyces species may form endospores, and while individual bacteria are rod-shaped, Actinomyces colonies form fungus-like branched networks of hyphae. [3] The aspect of these colonies initially led to the incorrect assumption that the organism was a fungus and to the name Actinomyces , "ray fungus" (from Greek actis , ray or beam, and mykes ...
Actinomycetoma is a chronic bacterial subcutaneous infection caused by Actinomyces that affect the skin and connective tissue. [1] It is, therefore, a form of actinomycosis . [ 2 ] Mycetoma is a broad term which includes actinomycetoma and eumycetoma under it.
Cutaneous actinomycosis is a chronic disease that affects the deep subcutaneous tissue of the skin. Caused by an anaerobic, Gram-positive, filamentous type of bacteria in the genus Actinomyces, [1]: 270 invasion of the soft tissue leads to the formation of abnormal channels leading to the skin surface (external sinus tracts) that discharge pale yellow sulfur granules.
It is one of the bacteria that might be implicated in destructive periodontal disease. Although it has been found more frequently in localized aggressive periodontitis, [3] prevalence in any population is rather high. It has also been isolated from actinomycotic lesions (mixed infection with certain Actinomyces species, in particular A. israelii).
Most are non-infectious, although there are some non-communicable infectious diseases, such as parasitic diseases in which the parasite's life cycle does not include direct host-to-host transmission. The four main NCDs that are the leading causes of death globally are cardiovascular disease , cancer , chronic respiratory diseases , and diabetes .
Noteworthy, the diagnosis of mycetoma in non-endemic or low endemic areas as Europe and North Africa is challenging. [ 5 ] [ 6 ] Physicians in these areas are usually unfamiliar with the disease-specific manifestations and need to exercise extra vigilance regarding those patients who are at high risk of contracting mycetoma infections. [ 7 ]
Actinomyces massiliensis is a non-spore forming, non-motile, Gram-positive, rod-shaped bacterium. [1] [2] Cells measure at 0.5-1.7 μm in length and 0.35-0.74 μm in width, and they appear as straight rods. [1] [2] When plated on sheep-blood agar, colonies of A. massiliensis are circular, white, and have a glossy sheen. [1]