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Thrombocyte/Platelet count (Plt) 140, [15] 150 [5] [14] 350, [5] [23] 400, [14] 450 [15] x10 9 /L or x1000/μL: Mean platelet volume (MPV) 7.2, [147] 7.4, [148] 7.5 [149] 10.4, [148] 11.5, [149] 11.7 [147] fL: Prothrombin time (PT) 10, [18] 11, [14] [150] 12 [15] 13, [18] 13.5, [150] 14, [15] 15 [14] s: PT reference varies between laboratory ...
RDW-CV "width" refers to the width of the volume curve (distribution width), not the width of the cells. [5] [6] RDW-SD is calculated as the width (in fL) of the RBC size distribution histogram at the 20% height level. This parameter is, therefore, not influenced by the average RBC size (mean corpuscular volume, MCV). [7]
Absolute neutrophil count (ANC) is a measure of the number of neutrophil granulocytes [1] (also known as polymorphonuclear cells, PMN's, polys, granulocytes, segmented neutrophils or segs) present in the blood.
Splenomegaly is an enlargement of the spleen. [1] The spleen usually lies in the left upper quadrant (LUQ) of the human abdomen.Splenomegaly is one of the four cardinal signs of hypersplenism which include: some reduction in number of circulating blood cells affecting granulocytes, erythrocytes or platelets in any combination; a compensatory proliferative response in the bone marrow; and the ...
It is clinically similar to a pericardial effusion, and, depending on the volume and rapidity with which it develops, may cause cardiac tamponade. [ 1 ] The condition can be caused by full-thickness necrosis (death) of the myocardium (heart muscle) after myocardial infarction , chest trauma , [ 2 ] and by over-prescription of anticoagulants .
HLA region of Chromosome 6. The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1]
Suspension cultures are easily passaged with a small amount of culture containing a few cells diluted in a larger volume of fresh media. For adherent cultures, cells first need to be detached; this is commonly done with a mixture of trypsin - EDTA ; however, other enzyme mixes are now available for this purpose.
14-3-3 proteins are a family of conserved regulatory molecules that are expressed in all eukaryotic cells. 14-3-3 proteins have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors.
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