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  2. Category:RNA polymerase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:RNA_polymerase...

    Pages in category "RNA polymerase inhibitors" The following 5 pages are in this category, out of 5 total. This list may not reflect recent changes. A. Α-Amanitin;

  3. RNA polymerase I - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase_I

    RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized by RNA polymerase III), a type of RNA that accounts for over 50% of the total RNA synthesized in a cell.

  4. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Ribonucleotide reductase and DNA polymerase inhibitor. [11] Acute lymphoblastic leukaemia and acute myeloid leukaemia: Myelosuppression, hypokalaemia, cytokine release syndrome, Stevens–Johnson syndrome (uncommon), toxic epidermal necrolysis (uncommon) and pancreatitis (uncommon) Cytarabine: SC, IM, IV, IT: DNA polymerase inhibitor, S-phase ...

  5. Polymerase chain reaction inhibitors - Wikipedia

    en.wikipedia.org/wiki/Polymerase_chain_reaction...

    PCR inhibitors are any factor which prevent the amplification of nucleic acids through the polymerase chain reaction (PCR). [1] PCR inhibition is the most common cause of amplification failure when sufficient copies of DNA are present. [2] PCR inhibitors usually affect PCR through interaction with DNA or interference with the DNA polymerase.

  6. Nucleic acid inhibitor - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_inhibitor

    Image illustrates DNA, RNA, and protein synthesis. The first two are nucleic acids. A nucleic acid inhibitor is a type of antibacterial that acts by inhibiting the production of nucleic acids. There are two major classes: DNA inhibitors and RNA inhibitors. [1] The antifungal flucytosine acts in a similar manner.

  7. Category:Enzyme inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:Enzyme_inhibitors

    RNA polymerase inhibitors (2 C, 5 P) S. Steroidogenesis inhibitors (19 C, 8 P) T. Topoisomerase inhibitors (2 C, 38 P) Transferase inhibitors (13 C, 6 P)

  8. RNA polymerase - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase

    In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that catalyzes the chemical reactions that synthesize RNA from a DNA template.

  9. Sofosbuvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir

    Tenofovir alafenamide—a nucleotide reverse-transcriptase inhibitor that uses similar phosphoramidate prodrug technology [92] [32] Remdesivir—a nucleotide analogue RNA polymerase inhibitor originally intended to treat hepatitis C that uses similar phosphoramidate prodrug technology and displays very similar PK.